Buy Epithalon Research Peptide
Epithalon is available as a lyophilised powder, independently HPLC and MS-UPLC tested to ≥98% purity.
Buy Epithalon Research Peptide
Epithalon is available as a lyophilised powder, independently HPLC and MS-UPLC tested to ≥98% purity.
HPLC Verified
≥98% purity
Lyophilised
Powder format
Express Shipping
Cold-chain included
COA Available
Every batch
HPLC Verified
≥98% purity
Lyophilised
Powder format
Express Shipping
Cold-chain included
COA Available
Every batch
Same or Next Day Dispatch
Order before 12pm GMT for same-day dispatch; after 12pm ships next business day
Same or Next Day Dispatch
Order before 12pm GMT for same-day dispatch; after 12pm ships next business day
What is Epithalon?
A synthetic four-amino-acid peptide modelled on a substance originally extracted from the pineal gland, Epitalon is studied largely in the context of cellular ageing. Research interest centres on its reported ability to activate telomerase, the enzyme that maintains the protective caps at the ends of chromosomes.
- In cultured human somatic cells, Epitalon was reported to induce telomerase activity and promote elongation of telomeres.
- In aged mouse cohorts, long-term administration was associated with reduced incidence of spontaneous tumours.
- Rodent studies describe normalisation of circadian melatonin rhythms following administration.
- In vitro work reports modulation of gene expression associated with cell proliferation and antioxidant defence.
For research use only. Not intended for human use.
As one of the shortest synthetic peptides actively investigated in telomere biology research, the tetrapeptide Epithalon occupies a singular position among compounds studied for their interaction with telomerase-associated pathways. Also known as Epitalon or Epithalamin (CAS 307297-39-8), this compound has the molecular formula C14H22N4O9 and a molecular weight of 390.35 g/mol. Its sequence Ala-Glu-Asp-Gly comprises four residues with no known direct receptor target. Produced via solid-phase peptide synthesis.
In vitro studies using human diploid fibroblast cultures approaching replicative senescence have investigated whether Epithalamin modulates hTERT promoter activity and enzymatic telomerase activity as measured by TRAP assay. In vivo rodent longevity models have examined the compound's influence on tissue-specific telomere length dynamics across serial sampling timepoints.
Manufactured in a quality-controlled laboratory to a guaranteed purity of 98% or above. Every batch undergoes independent third-party testing using HPLC and MS-UPLC analysis before dispatch. Vials are vacuum sealed and stored in a temperature-controlled, monitored cold storage system. A batch-specific Certificate of Analysis is available on request.
Sold strictly for in vitro research purposes only. Not for human consumption. Intended for use by qualified researchers in laboratory settings only.
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Quality Guaranteed
Every batch is HPLC-tested to ≥98% purity. Certificate of Analysis and SDS available on request.