Deslorelin

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Description

Pharmacokinetics

Deslorelin is a potent agonist of gonadotropin-releasing hormone receptors, or GnRHRs. As a synthetic analog of the usual signal carrier, gonadotropin-releasing hormone (GnRH), deslorelin works similarly. Upon reaching the receptors, which reside in cell membranes, deslorelin signals for the rapid release of luteinizing and follicle-stimulating hormones.[3] This either results in the depletion of these hormones, and lower levels of sex hormones, or when used short term, temporary boosts and benefits. 

Scientific Studies

Deslorelin’s effects have been noted in women in a 2011 study. The study was conducted on women with varying issues surrounding ovulation. Women who underwent treatment experienced a form of “pseudomenopause.” Effectively, periods temporarily ceased while undergoing deslorelin exposure and treatment.[3] Within male animal test subjects, decreased fertility rates have been noted. These effects were achieved with slow releasing implants however. [2]

Sources:

[1] https://www.fda.gov/animal-veterinary/product-safety-information/sucromate-equine-deslorelin-acetate-veterinarians

[2] https://www.ncbi.nlm.nih.gov/pubmed/25277434

[3] http://www.ijem.in/article.asp?issn=2230-8210;year=2011;volume=15;issue=4;spage=261;epage=267;aulast=Magon

[4] https://www.ncbi.nlm.nih.gov/pmc/articles/PMC2266963/

[5] http://www.jbc.org/content/285/33/25103

[6] https://www.karger.com/Article/Abstract/209352

Additional information

Weight 23 oz
Dimensions 12 × 31 × 23 in
Color
Size

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