Buy PT-141 (Bremelanotide) Research Peptide

Cyclic lactam architecture distinguishes PT-141 from linear melanocortin peptides and has made it one of the most structurally studied synthetic agonists at the MC3R and MC4R receptor subtypes. Also known as Bremelanotide (CAS 189691-06-3), carries the molecular formula C50H68N14O10S and a molecular weight of 1025.22 g/mol. Its sequence Ac-Nle-cyclo[Asp-His-D-Phe-Arg-Trp-Lys]-OH incorporates a norleucine substitution and a lactam bridge. Produced via solid-phase peptide synthesis.

In vitro functional assays using cells expressing individual melanocortin receptor subtypes have characterised the agonist potency of PT-141 at MC1R through MC5R. In vivo rodent models have investigated the central distribution and receptor occupancy of PT-141 following peripheral administration, examining whether the compound engages hypothalamic MC3R and MC4R populations.

Manufactured in a cGMP compliant, ISO9001 certified laboratory to a guaranteed purity of 98% or above. Every batch undergoes independent testing using HPLC and MS-UPLC analysis before dispatch. Vials are vacuum sealed and stored in a temperature controlled, monitored cold storage system. Certificates of Analysis are available on request.

Sold strictly for in vitro research purposes only. Not for human consumption. Intended for use by qualified researchers in laboratory settings only.