Buy PT-141 (Bremelanotide) Research Peptide

Cyclic lactam architecture distinguishes PT-141 from linear melanocortin peptides and has made it one of the most structurally studied synthetic agonists at the MC3R and MC4R receptor subtypes. Also known as Bremelanotide (CAS 189691-06-3), carries the molecular formula C50H68N14O10S and a molecular weight of 1025.22 g/mol. Its sequence Ac-Nle-cyclo[Asp-His-D-Phe-Arg-Trp-Lys]-OH incorporates a norleucine substitution and a lactam bridge. Produced via solid-phase peptide synthesis.

In vitro functional assays using cells expressing individual melanocortin receptor subtypes have characterised the agonist potency of PT-141 at MC1R through MC5R. In vivo rodent models have investigated the central distribution and receptor occupancy of PT-141 following peripheral administration, examining whether the compound engages hypothalamic MC3R and MC4R populations.

Manufactured in a quality-controlled laboratory to a guaranteed purity of 98% or above. Every batch undergoes independent third-party testing using HPLC and MS-UPLC analysis before dispatch. Vials are vacuum sealed and stored in a temperature-controlled, monitored cold storage system. A batch-specific Certificate of Analysis is available on request.

Sold strictly for in vitro research purposes only. Not for human consumption. Intended for use by qualified researchers in laboratory settings only.