ACTH 1-39 research peptide — ≥98% purity by HPLC — CAS 9002-60-2 — also known as Adrenocorticotropic Hormone, Corticotropin, ACTH — lyophilized powder for in-vitro laboratory research — Peptides.net
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Buy ACTH 1-39 Research Peptide

ACTH 1-39 is available as a lyophilised powder, independently HPLC and MS-UPLC tested to ≥98% purity.

4,541.10 g/mol≥98% (HPLC)9002-60-2

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≥98% purity

Lyophilised

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What is ACTH 1-39?

A synthetic 39-amino-acid polypeptide identical to the body's main trigger for stress-hormone release, ACTH 1-39 is studied as the principal regulator of adrenal hormone output. Research focuses on its signalling through the melanocortin-2 receptor and its unusual requirement for the accessory protein MRAP.

  • Studied for its signalling through the melanocortin-2 receptor (MC2R).
  • Investigated for its dependence on the accessory protein MRAP.
  • Examined in research models for its role in the hypothalamic-pituitary-adrenal axis.
  • Used as a research tool to study adrenal steroidogenesis pathways.

For research use only. Not intended for human use.

Comprising the full 39-amino acid sequence of the endogenous adrenocorticotropic hormone, ACTH 1-39 represents the complete pituitary-derived melanocortin peptide from which shorter active fragments are derived. Also known as Corticotropin (CAS 9002-60-2), this polypeptide has a molecular weight of 4541.14 g/mol. Produced via solid-phase peptide synthesis.

In vitro studies using MC2R-expressing adrenocortical cell lines co-transfected with the MC2R accessory protein (MRAP) have compared the binding kinetics and steroidogenic signalling output of Corticotropin against ACTH(1-24). In vivo rodent adrenal axis models have explored the comparative pharmacokinetics of full-length ACTH 1-39 and truncated fragments, examining susceptibility to circulating proteases.

Manufactured in a quality-controlled laboratory to a guaranteed purity of 98% or above. Every batch undergoes independent third-party testing using HPLC and MS-UPLC analysis before dispatch. Vials are vacuum sealed and stored in a temperature-controlled, monitored cold storage system. A batch-specific Certificate of Analysis is available on request.

Sold strictly for in vitro research purposes only. Not for human consumption. Intended for use by qualified researchers in laboratory settings only.

Scientific Review

Dr. Cristina Cosi

Scientific review

Dr. Cristina Cosi

Scientific Contributor and Reviewer

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Every batch is HPLC-tested to ≥98% purity. Certificate of Analysis and SDS available on request.

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