Buy P21 (P021) Research Peptide

Rational design based on the ciliary neurotrophic factor (CNTF) C-terminal domain produced P21, a small peptide mimetic that has attracted preclinical interest for its capacity to engage neurotrophic signalling pathways without requiring the full-length cytokine. Also designated P021 or CNTF peptide mimetic, approximate molecular weight of 500 g/mol. Produced via solid-phase peptide synthesis.

In vitro studies using primary hippocampal neuron cultures have examined whether P21 activates JAK/STAT3 and PI3K/Akt pathways downstream of the tripartite CNTF receptor. In vivo rodent models have investigated the oral bioavailability and CNS penetration of P21, examining whether this low-molecular-weight mimetic achieves central nervous system exposure sufficient to modulate dentate gyrus neurogenesis markers.

Manufactured in a quality-controlled laboratory to a guaranteed purity of 98% or above. Every batch undergoes independent third-party testing using HPLC and MS-UPLC analysis before dispatch. Vials are vacuum sealed and stored in a temperature-controlled, monitored cold storage system. A batch-specific Certificate of Analysis is available on request.

Sold strictly for in vitro research purposes only. Not for human consumption. Intended for use by qualified researchers in laboratory settings only.