Buy Humanin Research Peptide

Encoded within the mitochondrial 16S rRNA gene, Humanin is a 21-amino acid mitochondrial-derived peptide that challenged the prevailing assumption that functional open reading frames within mitochondrial rRNA genes were non-existent. Also designated HN or MTRNR2, approximate molecular weight of 2690 g/mol and the sequence MAPRGFSCLLLLTSEIDLPVKRRA. Produced via solid-phase peptide synthesis.

In vitro studies using neuronal cell lines exposed to apoptotic stimuli have investigated whether Humanin modulates Bax translocation to mitochondrial membranes and subsequent cytochrome c release through direct protein-protein interaction. In vivo rodent models have explored the receptor-mediated signalling axis of HN, examining its reported interaction with the CNTFR/WSX-1/gp130 tripartite receptor complex and downstream STAT3 phosphorylation.

Manufactured in a quality-controlled laboratory to a guaranteed purity of 98% or above. Every batch undergoes independent third-party testing using HPLC and MS-UPLC analysis before dispatch. Vials are vacuum sealed and stored in a temperature-controlled, monitored cold storage system. A batch-specific Certificate of Analysis is available on request.

Sold strictly for in vitro research purposes only. Not for human consumption. Intended for use by qualified researchers in laboratory settings only.