Buy NAD+ Research Compound

As the principal electron-carrying coenzyme in cellular redox metabolism, Nicotinamide Adenine Dinucleotide occupies a foundational position in bioenergetics and sirtuin signalling research that extends far beyond its classical role in intermediary metabolism. NAD+ (CAS 53-84-9) carries the molecular formula C21H27N7O14P2 and a molecular weight of 663.43 g/mol.

This dinucleotide comprises an adenine and a nicotinamide nucleotide linked via a pyrophosphate bridge, and functions as both a hydride acceptor in catabolic reactions and a co-substrate for NAD+-consuming enzymes including sirtuins and PARPs.

In vitro studies using isolated mitochondrial preparations and permeabilised cell systems have investigated the kinetics of NAD+ consumption by SIRT3 and PARP1, examining how the compartmentalised NAD+/NADH ratio influences deacetylase versus ADP-ribosyltransferase activity in competing enzymatic reactions. In vivo rodent models have explored tissue-specific NAD+ biosynthesis and salvage pathway flux using isotope-labelled precursors.

Manufactured in a quality-controlled laboratory to a guaranteed purity of 98% or above. Every batch undergoes independent third-party testing using HPLC and MS-UPLC analysis before dispatch. Vials are vacuum sealed and stored in a temperature-controlled, monitored cold storage system. A batch-specific Certificate of Analysis is available on request.

Sold strictly for in vitro research purposes only. Not for human consumption. Intended for use by qualified researchers in laboratory settings only.