ADAMAX research peptide — ≥98% purity by HPLC — CAS 114681-65-1 — also known as Ac-Semax-Ad, N-Acetyl Semax Adamantane — lyophilized powder for in-vitro laboratory research — Peptides.net
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Buy ADAMAX Research Peptide

ADAMAX is available as a lyophilised powder, independently HPLC and MS-UPLC tested to ≥98% purity.

1,032.24 g/mol≥98% (HPLC)114681-65-1

HPLC Verified

≥98% purity

Lyophilised

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What is ADAMAX?

A synthetic nine-amino-acid designer analogue of the peptide Semax, ADAMAX is studied for its effects on memory, learning and the survival of nerve cells. Research focuses on two structural additions, an acetyl cap and a rigid adamantane cage, that increase stability and the ability to cross membranes.

  • Studied for its modelling on the Semax peptide with added stability modifications.
  • Investigated in research models for neurotrophic signalling pathways.
  • Examined for its membrane permeability and metabolic stability versus parent peptides.
  • Used as a research tool to study neuronal survival mechanisms.

For research use only. Not intended for human use.

Building upon the ACTH(4-10) melanocortin fragment scaffold, the addition of both an N-terminal acetyl group and a C-terminal adamantylglycine residue produced ADAMAX, a structurally reinforced analogue designed for maximal enzymatic stability. Also known as N-Acetyl Semax Adamantylglycine, approximate molecular weight of 1000 g/mol. Produced via solid-phase peptide synthesis.

In vitro comparative degradation assays using serum and brain homogenate preparations have measured the proteolytic half-life of ADAMAX alongside ACTH(4-10)-Pro-Gly-Pro and unmodified ACTH(4-10), establishing a structure-stability hierarchy. In vivo rodent models have investigated whether the adamantylglycine modification alters CNS penetration or tissue distribution patterns compared to the parent compound.

Manufactured in a quality-controlled laboratory to a guaranteed purity of 98% or above. Every batch undergoes independent third-party testing using HPLC and MS-UPLC analysis before dispatch. Vials are vacuum sealed and stored in a temperature-controlled, monitored cold storage system. A batch-specific Certificate of Analysis is available on request.

Sold strictly for in vitro research purposes only. Not for human consumption. Intended for use by qualified researchers in laboratory settings only.

Scientific Review

Dr. Cristina Cosi

Scientific review

Dr. Cristina Cosi

Scientific Contributor and Reviewer

Currently under review

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Every batch is HPLC-tested to ≥98% purity. Certificate of Analysis and SDS available on request.

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