Buy Oxytocin Research Peptide

As a cyclic nonapeptide containing an internal disulphide bridge between cysteine residues at positions 1 and 6, Oxytocin has served as a structural archetype in neurohypophyseal peptide research for over half a century. Also designated OXT (CAS 50-56-6), it carries the molecular formula C₄₃H₆₆N₁₂O₁₂S₂ and a molecular weight of 1007.19 g/mol. Produced via solid-phase peptide synthesis, it acts at the oxytocin receptor (OXTR), a Gq-coupled GPCR.

In the rat brain, oxytocinergic projections from neurons of the parvocellular nucleus (PVN) and of the supraoptic nucleus (SON) of the hypothalamus release oxytocin (OXY) in brain areas related to the reward circuitry, ventral tegmental area (VTA) and nucleus accumbens, to the stress circuitry, hippocampus, amygdala and PVN, and to the maternal functions circuitry, medial preoptic area and olfactory bulb. These projections are believed to be critical for appropriate social interactions. Evidence in rodents demonstrated that OXY induces prosocial behaviour through direct effects on the dopaminergic neurons of the VTA, providing insight into how social interactions can generate rewarding experiences.^[1] Oxytocin administered centrally in rodent models reduced stress effects on hippocampal synaptic plasticity and memory via acting on oxytocin receptors and regulating ERK activity.^[2] OXY receptor mRNA and autoradiographic binding are higher in the VTA and mPOA of postpartum rats, and inhibition by site-specific OXY receptor antagonist in either brain area impairs caregiving in recently parturient dams.^[3]

Manufactured in a quality-controlled, ISO9001 certified laboratory to a guaranteed purity of 98% or above. Every batch undergoes independent third-party testing using HPLC and MS-UPLC analysis before dispatch. Vials are vacuum sealed and stored in a temperature-controlled, monitored cold storage system. A batch-specific Certificate of Analysis is available on request.

Sold strictly for in vitro research purposes only. Not for human consumption. Intended for use by qualified researchers in laboratory settings only.