PEG-MGF research peptide — ≥98% purity by HPLC — CAS N/A (PEGylated conjugate) — also known as PEGylated Mechano Growth Factor, PEG-IGF-1Ec — lyophilized powder for in-vitro laboratory research — Peptides.net
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Buy PEG-MGF Research Peptide

PEG-MGF is available as a lyophilised powder, independently HPLC and MS-UPLC tested to ≥98% purity.

~4,000–5,000 g/mol (variable PEG chain)≥98% (HPLC)N/A (PEGylated conjugate)

HPLC Verified

≥98% purity

Lyophilised

Powder format

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What is PEG-MGF?

A version of Mechano Growth Factor attached to a polyethylene glycol chain to slow its breakdown, PEG-MGF is studied as a longer-lasting muscle-repair peptide. Research focuses on how the modification extends circulating stability while the E-domain retains its signalling activity.

  • Studied for the extended stability provided by PEGylation.
  • Investigated in research models for E-domain signalling.
  • Examined for muscle-cell and cardiac-tissue activity in vitro.
  • Used as a research tool to study longer-acting MGF analogues.

For research use only. Not intended for human use.

Covalent attachment of a polyethylene glycol chain to the C-terminal fragment of mechano growth factor created a structurally modified analogue designed to resist rapid proteolytic degradation. PEG-MGF, also known as PEGylated Mechano Growth Factor, has an approximate molecular weight of 4500 g/mol. The PEGylation shields the native peptide sequence from enzymatic cleavage. Produced via solid-phase peptide synthesis followed by site-specific PEGylation.

In vitro studies using C2C12 myoblast cultures have examined whether PEG-MGF activates IGF-1R and downstream Akt/mTOR cascades with different kinetic profiles compared to its unconjugated counterpart. In vivo rodent models have explored the biodistribution and serum persistence of PEGylated Mechano Growth Factor relative to unmodified MGF.

Manufactured in a quality-controlled laboratory to a guaranteed purity of 98% or above. Every batch undergoes independent third-party testing using HPLC and MS-UPLC analysis before dispatch. Vials are vacuum sealed and stored in a temperature-controlled, monitored cold storage system. A batch-specific Certificate of Analysis is available on request.

Sold strictly for in vitro research purposes only. Not for human consumption. Intended for use by qualified researchers in laboratory settings only.

Scientific Review

Dr. Cristina Cosi

Scientific review

Dr. Cristina Cosi

Scientific Contributor and Reviewer

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£21.95
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Batch-specific Certificate of Analysis available on request

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Every batch is HPLC-tested to ≥98% purity. Certificate of Analysis and SDS available on request.

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