Buy MGF (Mechano Growth Factor) Research Peptide
MGF is available as a lyophilised powder, independently HPLC and MS-UPLC tested to ≥98% purity. A batch-specific Certificate of Analysis is available on request.
Buy MGF (Mechano Growth Factor) Research Peptide
MGF is available as a lyophilised powder, independently HPLC and MS-UPLC tested to ≥98% purity. A batch-specific Certificate of Analysis is available on request.
HPLC Verified
≥98% purity
Lyophilised
Powder format
Express Shipping
Cold-chain included
COA Available
Every batch
Same or Next Day Dispatch
Order before 12pm GMT for same-day dispatch; after 12pm ships next business day
HPLC Verified
≥98% purity
Lyophilised
Powder format
Express Shipping
Cold-chain included
COA Available
Every batch
Same or Next Day Dispatch
Order before 12pm GMT for same-day dispatch; after 12pm ships next business day
What is MGF (Mechano Growth Factor)?
A synthetic 24-amino-acid peptide corresponding to a splice variant of insulin-like growth factor 1 that the body produces after muscle is strained, MGF is studied for its role in muscle repair. Research focuses on how its E-domain signals differently from mature insulin-like growth factor 1, affecting muscle cell proliferation and timing.
- Studied for the distinct signalling of its E-domain versus mature IGF-1.
- Investigated in research models for muscle-cell proliferation.
- Examined for its role in the response of muscle to mechanical strain.
- Used as a research tool to study satellite-cell activation.
For research use only. Not intended for human use.
Differential splicing of the IGF-1 gene under mechanical load conditions produces a distinct C-terminal peptide significant in IGF-1 biology. MGF, also known as Mechano Growth Factor or IGF-1Ec, is a 24-amino acid fragment with a molecular weight of 2867.26 g/mol. Produced via solid-phase peptide synthesis.
In vitro studies using satellite cell isolates have investigated whether MGF activates proliferative cascades through mechanisms distinct from those initiated by mature IGF-1, with particular attention to ERK1/2 phosphorylation patterns. In vivo rodent models have explored the temporal expression profile of endogenous IGF-1Ec mRNA following mechanical loading protocols.
Manufactured in a quality-controlled laboratory to a guaranteed purity of 98% or above. Every batch undergoes independent third-party testing using HPLC and MS-UPLC analysis before dispatch. Vials are vacuum sealed and stored in a temperature-controlled, monitored cold storage system. A batch-specific Certificate of Analysis is available on request.
Sold strictly for in vitro research purposes only. Not for human consumption. Intended for use by qualified researchers in laboratory settings only.
Scientific Review
Scientific review
Dr. Cristina Cosi
Scientific Contributor and Reviewer
Currently under review
What Researchers Say
Sign in to leave a reviewNo reviews yet. Be the first to share your research experience.
Frequently Asked Questions
Select Size
Quality Guaranteed
Every batch is HPLC-tested to ≥98% purity. Certificate of Analysis and SDS available on request.