Buy GHRP-6 Research Peptide
GHRP-6 is available as a lyophilised powder, independently HPLC and MS-UPLC tested to ≥98% purity. Every order ships with a batch-specific Certificate of Analysis.
Buy GHRP-6 Research Peptide
GHRP-6 is available as a lyophilised powder, independently HPLC and MS-UPLC tested to ≥98% purity. Every order ships with a batch-specific Certificate of Analysis.
HPLC Verified
≥98% purity
Lyophilised
Powder format
Express Shipping
Cold-chain included
COA Included
Every batch
Ships Next Day
Order before midnight. Dispatched tomorrow with cold-chain packaging
HPLC Verified
≥98% purity
Lyophilised
Powder format
Express Shipping
Cold-chain included
COA Included
Every batch
Ships Next Day
Order before midnight. Dispatched tomorrow with cold-chain packaging
What is GHRP-6?
One of the earliest synthetic growth hormone secretagogues to be characterised, GHRP-6 is a six-amino-acid peptide studied as a benchmark for stimulating growth hormone release. Research focuses on its activation of the ghrelin receptor and the downstream signalling that drives secretion from the pituitary.
- In ovine and rat somatotroph cultures, GHRP-6 induced growth hormone release dependent on intracellular cAMP and voltage-gated calcium channels.
- Rodent studies describe synergy with growth hormone-releasing hormone in modulating growth hormone pulse amplitude.
- Investigations report a cytoprotective effect in cardiac tissue independent of growth hormone release.
- Receptor work establishes its role as a foundational comparator for second and third generation secretagogues.
For research use only. Not intended for human use.
Among the earliest synthetic hexapeptides developed for ghrelin receptor research, Growth Hormone-Releasing Peptide-6 has remained a foundational compound in preclinical secretagogue pharmacology. GHRP-6 (CAS 87616-84-0) carries the molecular formula C46H56N12O6 and a molecular weight of 873.01 g/mol. Its sequence His-D-Trp-Ala-Trp-D-Phe-Lys-NH2 features a D-Tryptophan substitution at position 2, central to its recognition at GHS-R1a. Produced via solid-phase peptide synthesis.
In vitro studies using isolated pituitary preparations have examined the capacity to initiate intracellular calcium flux and phosphoinositide turnover upon GHS-R1a engagement. In vivo rodent models have explored the interplay between GHRP-6 administration and hypothalamic neuropeptide circuits, particularly regarding orexigenic signalling pathways.
Manufactured in a cGMP compliant laboratory to a guaranteed purity of 98% or above. Every batch undergoes independent testing using HPLC and MS-UPLC analysis before dispatch. Vials are vacuum sealed and stored in a temperature controlled, monitored cold storage system. Certificates of Analysis are available on request.
Sold strictly for in vitro research purposes only. Not for human consumption. Intended for use by qualified researchers in laboratory settings only.
Editorial Team
Scientific review
Dr. Cristina Cosi, PhD
Scientific Contributor and Reviewer
Currently under review
What Researchers Say
Sign in to leave a reviewNo reviews yet. Be the first to share your research experience.
Frequently Asked Questions
Related Compounds
Select Size
Add 5 or more to unlock discounts
Quality Guaranteed
Every batch is HPLC-tested to ≥99% purity. Certificate of Analysis and MSDS available with every order.