Buy IGF-1 LR3 Research Peptide

Extension of the native insulin-like growth factor-1 sequence by 13 amino acids and substitution of glutamic acid-3 with arginine produced a structurally distinct analogue central to IGF-1 receptor signalling studies. IGF-1 LR3, also known as Long R3 IGF-1 (CAS 946870-92-4), is an 83-amino acid peptide with a molecular weight of 9117.55 g/mol. These modifications reduce affinity for IGF-binding proteins. Produced via solid-phase peptide synthesis.

In vitro studies using cell lines expressing IGF-1R have investigated Akt/PKB and PI3K pathway activation in the relative absence of IGFBP interference. In vivo rodent models have explored tissue-specific IGF-1R engagement by comparing the biodistribution and signalling footprint of IGF-1 LR3 against the native 70-amino acid ligand.

Manufactured in a cGMP compliant laboratory to a guaranteed purity of 98% or above. Every batch undergoes independent testing using HPLC and MS-UPLC analysis before dispatch. Vials are vacuum sealed and stored in a temperature controlled, monitored cold storage system. Certificates of Analysis are available on request.

Sold strictly for in vitro research purposes only. Not for human consumption. Intended for use by qualified researchers in laboratory settings only.