Buy Snap-8 Research Peptide

Extension of the hexapeptide SNARE-targeting approach to an octapeptide format produced Snap-8, a compound designed to investigate synaptic vesicle fusion machinery at a distinct point in the exocytotic signalling cascade. Also known as Acetyl Octapeptide-3 or Leuphasyl (CAS 868844-74-0), carries the molecular formula C41H70N16O13 and a molecular weight of 983.10 g/mol. Its sequence Ac-Glu-Glu-Met-Gln-Arg-Arg-Ala-Asp-NH2 mimics a region of the SNAP-25 protein. Produced via solid-phase peptide synthesis.

In vitro reconstituted SNARE assembly assays have examined whether Leuphasyl competes with endogenous SNAP-25 for binding to syntaxin-1A, measuring competitive displacement using FRET readouts. In vivo rodent neuromuscular junction preparations have explored whether Snap-8 modulates vesicle fusion frequency at the presynaptic terminal.

Manufactured in a quality-controlled laboratory to a guaranteed purity of 98% or above. Every batch undergoes independent third-party testing using HPLC and MS-UPLC analysis before dispatch. Vials are vacuum sealed and stored in a temperature-controlled, monitored cold storage system. A batch-specific Certificate of Analysis is available on request.

Sold strictly for in vitro research purposes only. Not for human consumption. Intended for use by qualified researchers in laboratory settings only.