Matrixyl research peptide — ≥98% purity by HPLC — CAS 214047-00-4 — also known as Palmitoyl Pentapeptide-4, Palmitoyl Pentapeptide-3, Pal-KTTKS — lyophilized powder for in-vitro laboratory research — Peptides.net
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Buy Matrixyl Research Peptide

Matrixyl is available as a lyophilised powder, independently HPLC and MS-UPLC tested to ≥98% purity.

802.06 g/mol≥98% (HPLC)214047-00-4

HPLC Verified

≥98% purity

Lyophilised

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What is Matrixyl?

A synthetic peptide built from a collagen fragment attached to a fatty-acid chain, also known as palmitoyl pentapeptide-4, Matrixyl is studied for its matrikine signalling and effects on collagen production in vitro. Research focuses on its role as a matrikine, a signal that prompts skin cells to increase production of structural proteins.

  • Studied in fibroblast cultures for its matrikine signalling.
  • Investigated for its effects on collagen gene expression in vitro.
  • Examined for its prompting of extracellular-matrix protein synthesis.
  • Used as a research tool in skin-cell model studies.

For research use only. Not intended for human use.

Identification of the pentapeptide KTTKS as a fragment of the type I procollagen C-terminal propeptide, followed by N-terminal palmitoylation, positioned Matrixyl as a structurally defined research tool in extracellular matrix feedback signalling. Also known as Palmitoyl Pentapeptide-4 or Pal-KTTKS (CAS 214047-00-4), carries the molecular formula C36H69N5O7S and a molecular weight of 701.04 g/mol. Produced via solid-phase peptide synthesis.

In vitro studies using primary dermal fibroblast cultures have investigated whether Matrixyl activates TGF-beta/SMAD-dependent transcriptional pathways governing collagen and glycosaminoglycan synthesis. In vivo rodent skin models have explored the penetration depth and dermal bioavailability of Palmitoyl Pentapeptide-4.

Manufactured in a quality-controlled laboratory to a guaranteed purity of 98% or above. Every batch undergoes independent third-party testing using HPLC and MS-UPLC analysis before dispatch. Vials are vacuum sealed and stored in a temperature-controlled, monitored cold storage system. A batch-specific Certificate of Analysis is available on request.

Sold strictly for in vitro research purposes only. Not for human consumption. Intended for use by qualified researchers in laboratory settings only.

Scientific Review

Dr. Cristina Cosi

Scientific review

Dr. Cristina Cosi

Scientific Contributor and Reviewer

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Every batch is HPLC-tested to ≥98% purity. Certificate of Analysis and SDS available on request.

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