Buy CJC-1295 (No DAC) Research Peptide
CJC-1295 (No DAC) is available as a lyophilised powder, independently HPLC and MS-UPLC tested to ≥98% purity.
Buy CJC-1295 (No DAC) Research Peptide
CJC-1295 (No DAC) is available as a lyophilised powder, independently HPLC and MS-UPLC tested to ≥98% purity.
HPLC Verified
≥98% purity
Lyophilised
Powder format
Express Shipping
Cold-chain included
COA Available
Every batch
Same or Next Day Dispatch
Order before 12pm GMT for same-day dispatch; after 12pm ships next business day
HPLC Verified
≥98% purity
Lyophilised
Powder format
Express Shipping
Cold-chain included
COA Available
Every batch
Same or Next Day Dispatch
Order before 12pm GMT for same-day dispatch; after 12pm ships next business day
What is CJC-1295 (No DAC)?
A synthetic analogue of growth hormone-releasing hormone modified at four positions to resist enzymatic breakdown, CJC-1295 without DAC is studied for its effect on growth hormone secretion. Research examines its relatively short duration of action, which mimics the natural pulsing pattern of growth hormone release.
- In rat anterior pituitary cells, the peptide stimulated adenylate cyclase activity and intracellular cAMP accumulation at the GHRH receptor.
- Rodent studies report growth hormone release patterns consistent with episodic, pulsatile signalling.
- Combination studies describe synergistic effects when co-administered with ghrelin-mimetic secretagogues such as GHRP-6.
- Pharmacokinetic work characterises its rapid clearance relative to the DAC-conjugated variant.
For research use only. Not intended for human use.
Strategic amino acid substitutions at protease-vulnerable positions within the native GHRH(1-29) sequence produced one of the most widely utilised modified fragments in growth hormone-releasing hormone receptor research. CJC-1295 (No DAC), commonly referred to as Mod GRF 1-29 (CAS 863288-34-0), is a 29-amino acid peptide with a molecular weight of 3360.00 g/mol. Produced via solid-phase peptide synthesis.
In vitro degradation assays using serum and purified dipeptidyl peptidase-IV preparations have quantified the compound's resistance to proteolytic cleavage relative to unmodified Sermorelin. Rodent in vivo models have examined whether the extended metabolic stability of CJC-1295 (No DAC) translates to altered temporal patterns of cAMP-mediated signalling at pituitary somatotroph populations.
Manufactured in a quality-controlled laboratory to a guaranteed purity of 98% or above. Every batch undergoes independent third-party testing using HPLC and MS-UPLC analysis before dispatch. Vials are vacuum sealed and stored in a temperature-controlled, monitored cold storage system. A batch-specific Certificate of Analysis is available on request.
Sold strictly for in vitro research purposes only. Not for human consumption. Intended for use by qualified researchers in laboratory settings only.
Scientific Review
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Dr. Cristina Cosi
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Frequently Asked Questions
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Quality Guaranteed
Every batch is HPLC-tested to ≥98% purity. Certificate of Analysis and SDS available on request.