CJC-1295 With DAC research peptide — ≥98% purity by HPLC — CAS 863288-34-0 — also known as CJC-1295 DAC, GHRH Analogue with Drug Affinity Complex — lyophilized powder for in-vitro laboratory research — Peptides.net
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Buy CJC-1295 With DAC Research Peptide

CJC-1295 With DAC is available as a lyophilised powder, independently HPLC and MS-UPLC tested to ≥98% purity.

3,647.28 g/mol≥98% (HPLC)863288-34-0

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≥98% purity

Lyophilised

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What is CJC-1295 With DAC?

A synthetic analogue of growth hormone-releasing hormone fitted with a Drug Affinity Complex that binds to blood albumin, CJC-1295 with DAC is studied for its extended duration of action. Research focuses on how albumin binding prolongs circulating half-life and sustains activation of the growth hormone-releasing hormone receptor.

  • Pharmacokinetic studies in rodents document prolonged circulating peptide concentrations following a single administration.
  • In rat pituitary somatotroph preparations, the peptide bound the GHRH receptor and triggered cAMP-mediated signalling.
  • Research characterises albumin-peptide dissociation kinetics as the basis for extended receptor occupancy.
  • Comparative work contrasts its sustained action with the pulsatile profile of the non-DAC variant.

For research use only. Not intended for human use.

Conjugation of a Drug Affinity Complex to a synthetic GHRH analogue introduced an entirely new pharmacokinetic dimension to growth hormone-releasing hormone receptor research. CJC-1295 With DAC, also designated DAC:GRF (CAS 863288-34-0), is a 30-amino acid peptide with a molecular weight of 3647.28 g/mol. The DAC moiety facilitates covalent binding to circulating albumin. Produced via solid-phase peptide synthesis.

In vitro albumin conjugation assays have investigated the kinetics and efficiency of covalent complex formation under varying physiological conditions. In vivo rodent studies have explored the pharmacokinetic profile of CJC-1295 With DAC relative to unconjugated GHRH analogues, examining plasma half-life extension.

Manufactured in a quality-controlled laboratory to a guaranteed purity of 98% or above. Every batch undergoes independent third-party testing using HPLC and MS-UPLC analysis before dispatch. Vials are vacuum sealed and stored in a temperature-controlled, monitored cold storage system. A batch-specific Certificate of Analysis is available on request.

Sold strictly for in vitro research purposes only. Not for human consumption. Intended for use by qualified researchers in laboratory settings only.

Scientific Review

Dr. Cristina Cosi

Scientific review

Dr. Cristina Cosi

Scientific Contributor and Reviewer

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Every batch is HPLC-tested to ≥98% purity. Certificate of Analysis and SDS available on request.

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