KPV research peptide — ≥98% purity by HPLC — CAS 67727-97-3 — also known as Lys-Pro-Val, α-MSH C-terminal tripeptide, ACTH 11-13 — lyophilized powder for in-vitro laboratory research — Peptides.net
HPLC Verified

Buy KPV Research Peptide

KPV is available as a lyophilised powder, independently HPLC and MS-UPLC tested to ≥98% purity.

328.41 g/mol≥98% (HPLC)67727-97-3

HPLC Verified

≥98% purity

Lyophilised

Powder format

Express Shipping

Cold-chain included

COA Available

Every batch

Same or Next Day Dispatch

Order before 12pm GMT for same-day dispatch; after 12pm ships next business day

What is KPV?

A synthetic three-amino-acid peptide taken from the tail end of the hormone alpha-MSH, KPV is studied for its anti-inflammatory effects, particularly in the gut. Research focuses on how it dampens inflammatory signalling without the pigment-related effects of the full hormone.

  • Studied for its anti-inflammatory signalling in gut-tissue models.
  • Investigated in vitro for its modulation of inflammatory pathways.
  • Examined for activity without the pigmentary effects of full alpha-MSH.
  • Used as a research tool to study intestinal inflammation models.

For research use only. Not intended for human use.

Representing the minimal C-terminal tripeptide fragment of alpha-melanocyte-stimulating hormone, KPV has attracted preclinical attention for its activity in signalling pathways distinct from classical melanocortin receptor engagement. Also designated Alpha-MSH(11-13), carries the molecular formula C20H34N6O5 and a molecular weight of 438.52 g/mol. Its sequence Lys-Pro-Val comprises the final three residues of the alpha-MSH tridecapeptide. Produced via solid-phase peptide synthesis.

In vitro studies using NF-kB luciferase reporter systems have investigated whether Alpha-MSH(11-13) modulates inflammatory transcription factor activation through direct intracellular uptake and nuclear translocation rather than cell-surface receptor engagement. In vivo rodent models have examined the biodistribution of radiolabelled KPV to determine whether the tripeptide accumulates in tissues with high inflammatory signalling burden.

Manufactured in a quality-controlled laboratory to a guaranteed purity of 98% or above. Every batch undergoes independent third-party testing using HPLC and MS-UPLC analysis before dispatch. Vials are vacuum sealed and stored in a temperature-controlled, monitored cold storage system. A batch-specific Certificate of Analysis is available on request.

Sold strictly for in vitro research purposes only. Not for human consumption. Intended for use by qualified researchers in laboratory settings only.

Scientific Review

Dr. Cristina Cosi

Scientific review

Dr. Cristina Cosi

Scientific Contributor and Reviewer

Currently under review

View credentials

What Researchers Say

Sign in to leave a review

No reviews yet. Be the first to share your research experience.

Frequently Asked Questions

Select Size

Quantity

Quantity

vial

1

Need larger quantities? Contact us for bulk pricing

£30.00
In Stock. Ships Next Business Day
Secure Checkout
VISA
Independent HPLC purity verification on every batch
Dispatched next business day with cold-chain delivery
Temperature-controlled packaging from lab to door
Batch-specific Certificate of Analysis available on request

Quality Guaranteed

Every batch is HPLC-tested to ≥98% purity. Certificate of Analysis and SDS available on request.

Your Cart

Your cart is empty

Add some research compounds to get started.

Browse Products