Buy B7-33 Research Peptide

Reduction of the two-chain disulphide-bonded relaxin-2 structure to a single 26-amino acid chain produced B7-33, a minimalist agonist that has become a central tool for investigating biased signalling at the relaxin family peptide receptor 1 (RXFP1). Also designated RXFP1 biased agonist, approximate molecular weight of 2800 g/mol. Produced via solid-phase peptide synthesis.

In vitro studies using RXFP1-expressing HEK293 cells have compared the signalling fingerprint of B7-33 against native relaxin-2, examining differential activation of cAMP accumulation, ERK1/2 phosphorylation and beta-arrestin recruitment. In vivo rodent fibrosis models have investigated whether the biased signalling profile of B7-33 produces a pathway activation pattern distinct from that of full-length relaxin-2.

Manufactured in a quality-controlled laboratory to a guaranteed purity of 98% or above. Every batch undergoes independent third-party testing using HPLC and MS-UPLC analysis before dispatch. Vials are vacuum sealed and stored in a temperature-controlled, monitored cold storage system. A batch-specific Certificate of Analysis is available on request.

Sold strictly for in vitro research purposes only. Not for human consumption. Intended for use by qualified researchers in laboratory settings only.