Fragment 176-191
HPLC Verified

Buy Fragment 176-191 Research Peptide

Fragment 176-191 is available as a lyophilised powder, independently HPLC and MS-UPLC tested to ≥98% purity. Every order ships with a batch-specific Certificate of Analysis.

1,815.12 g/mol≥98% (HPLC)66004-57-7

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≥98% purity

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What is Fragment 176-191?

A synthetic 16-amino-acid peptide corresponding to the tail region of human growth hormone, HGH Fragment 176-191 is studied for fat-related metabolism without growth effects. Research focuses on the finding that it does not activate the growth hormone receptor or affect insulin-like growth factor signalling.

  • Studied for supporting fat loss and weight management.
  • Researched for boosting the body's fat-burning activity.
  • Examined for promoting fat breakdown without affecting blood sugar or growth.
  • Studied for its targeted effects on body fat.

For research use only. Not intended for human use.

Isolation of a 16-amino acid C-terminal region from the full-length growth hormone sequence produced a peptide fragment with a distinct signalling profile. Fragment 176-191, also referred to as HGH Frag 176-191 (CAS 66004-57-7), carries the molecular formula C78H123N23O23S2 and a molecular weight of 1815.13 g/mol. Produced via solid-phase peptide synthesis.

In vitro studies using adipocyte cell models have investigated the compound's interaction with lipolytic signalling cascades, exploring whether HGH Frag 176-191 activates beta-adrenergic-adjacent pathways without engaging the JAK2/STAT5 axis. In vivo rodent models have examined the pharmacokinetic profile and tissue-specific distribution of the fragment relative to full-length recombinant growth hormone.

Manufactured in a cGMP compliant laboratory to a guaranteed purity of 98% or above. Every batch undergoes independent testing using HPLC and MS-UPLC analysis before dispatch. Vials are vacuum sealed and stored in a temperature controlled, monitored cold storage system. Certificates of Analysis are available on request.

Sold strictly for in vitro research purposes only. Not for human consumption. Intended for use by qualified researchers in laboratory settings only.

Editorial Team

Dr. Cristina Cosi, PhD

Scientific review

Dr. Cristina Cosi, PhD

Scientific Contributor and Reviewer

Currently under review

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