Buy ACE-031 Research Peptide
ACE-031 is available as a lyophilised powder, independently HPLC and MS-UPLC tested to ≥98% purity. Every order ships with a batch-specific Certificate of Analysis.
Buy ACE-031 Research Peptide
ACE-031 is available as a lyophilised powder, independently HPLC and MS-UPLC tested to ≥98% purity. Every order ships with a batch-specific Certificate of Analysis.
HPLC Verified
≥98% purity
Lyophilised
Powder format
Express Shipping
Cold-chain included
COA Included
Every batch
Ships Next Day
Order before midnight. Dispatched tomorrow with cold-chain packaging
HPLC Verified
≥98% purity
Lyophilised
Powder format
Express Shipping
Cold-chain included
COA Included
Every batch
Ships Next Day
Order before midnight. Dispatched tomorrow with cold-chain packaging
What is ACE-031?
A recombinant fusion protein that acts as a molecular sponge, also known as ActRIIB-Fc, ACE-031 is studied for its effects on skeletal muscle mass. Research focuses on how it traps several growth-regulating proteins at once, including myostatin, rather than blocking a single target.
- Studied for its activity as a soluble decoy at the activin type II receptor (ActRIIB).
- Investigated in research models for its binding of myostatin and related TGF-beta ligands.
- Examined for its capacity to sequester several growth-regulating ligands at once.
- Used as a research tool to study the myostatin signalling axis in skeletal muscle models.
For research use only. Not intended for human use.
Fusion of the extracellular domain of the activin type IIB receptor to an immunoglobulin Fc fragment created a soluble decoy receptor central to TGF-beta ligand-trapping research. ACE-031, also designated ACVR2B-Fc or ActRIIB-Fc, is a recombinant fusion protein with an approximate molecular weight of 60,000 g/mol. Produced as a recombinant protein.
In vitro surface plasmon resonance assays have measured the binding kinetics of ACE-031 against a panel of TGF-beta ligands including GDF-8, GDF-11, activin A and activin B. In vivo rodent models have investigated the downstream consequences of broad-spectrum ligand sequestration by ActRIIB-Fc on SMAD2/3 phosphorylation status across multiple tissue types.
Manufactured in a quality-controlled laboratory to a guaranteed purity of 98% or above. Every batch undergoes independent testing using HPLC and MS-UPLC analysis before dispatch. Vials are vacuum sealed and stored in a temperature controlled, monitored cold storage system. Certificates of Analysis are available on request.
Sold strictly for in vitro research purposes only. Not for human consumption. Intended for use by qualified researchers in laboratory settings only.
Editorial Team
Scientific review
Dr. Cristina Cosi, PhD
Scientific Contributor and Reviewer
Currently under review
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Every batch is HPLC-tested to ≥99% purity. Certificate of Analysis and MSDS available with every order.