Buy IGF-1 LR3 Research Protein

Extension of the native insulin-like growth factor-1 sequence by 13 amino acids and substitution of glutamic acid-3 with arginine produced a structurally distinct analogue central to IGF-1 receptor signalling studies. IGF-1 LR3, also known as Long R3 IGF-1 (CAS 946870-92-4), is an 83-amino acid peptide with a molecular weight of 9117.55 g/mol. These modifications reduce affinity for IGF-binding proteins. Produced via solid-phase peptide synthesis.

In vitro studies using cell lines expressing IGF-1R have investigated Akt/PKB and PI3K pathway activation in the relative absence of IGFBP interference. In vivo rodent models have explored tissue-specific IGF-1R engagement by comparing the biodistribution and signalling footprint of IGF-1 LR3 against the native 70-amino acid ligand.

Manufactured in a quality-controlled laboratory to a guaranteed purity of 98% or above. Every batch undergoes independent third-party testing using HPLC and MS-UPLC analysis before dispatch. Vials are vacuum sealed and stored in a temperature-controlled, monitored cold storage system. A batch-specific Certificate of Analysis is available on request.

Sold strictly for in vitro research purposes only. Not for human consumption. Intended for use by qualified researchers in laboratory settings only.