Ipamorelin
HPLC Verified

Buy Ipamorelin Research Peptide

Ipamorelin is available as a lyophilised powder, independently HPLC and MS-UPLC tested to ≥98% purity. A batch-specific Certificate of Analysis is available on request.

711.85 g/mol≥98% (HPLC)170851-70-4

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HPLC Verified

≥98% purity

Lyophilised

Powder format

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Cold-chain included

COA Available

Every batch

What is Ipamorelin?

A synthetic five-amino-acid peptide belonging to the growth hormone secretagogue class, Ipamorelin is studied for its ability to prompt the pituitary gland to release growth hormone. Research highlights its selectivity, acting on the ghrelin receptor without raising stress hormones such as cortisol.

  • In rat pituitary cell preparations, Ipamorelin stimulated growth hormone release without concurrent elevation of ACTH or cortisol.
  • Comparative secretagogue studies position it as more selective than GHRP-6 and GHRP-2 in preclinical panels.
  • In rodent studies, administration was associated with increased longitudinal bone growth.
  • Receptor pharmacology work characterises its action as a selective agonist at the GHS-R1a receptor.

For research use only. Not intended for human use.

Selectivity at the ghrelin receptor has become a defining research criterion for newer-generation growth hormone secretagogues, and Ipamorelin represents one of the most structurally refined compounds studied in this context. Also known as NNC 26-0161 (CAS 170851-70-4), this pentapeptide carries the molecular formula C38H49N9O5 and a molecular weight of 711.86 g/mol. Its sequence Aib-His-D-2-Nal-D-Phe-Lys-NH2 incorporates an alpha-aminoisobutyric acid residue at position 1. Produced via solid-phase peptide synthesis.

In vitro studies using clonal pituitary cell lines have compared intracellular signalling cascades initiated by Ipamorelin against those triggered by hexapeptide analogues, examining differential activation of IP3/DAG and cAMP-dependent pathways. In vivo rodent investigations have explored whether NNC 26-0161 engages hypothalamic appetite-regulatory circuits to the same degree as less selective secretagogues.

Manufactured in a quality-controlled laboratory to a guaranteed purity of 98% or above. Every batch undergoes independent third-party testing using HPLC and MS-UPLC analysis before dispatch. Vials are vacuum sealed and stored in a temperature-controlled, monitored cold storage system. A batch-specific Certificate of Analysis is available on request.

Sold strictly for in vitro research purposes only. Not for human consumption. Intended for use by qualified researchers in laboratory settings only.

Scientific Review

Dr. Cristina Cosi

Scientific review

Dr. Cristina Cosi

Scientific Contributor and Reviewer

Currently under review

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£9.95
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Independent HPLC purity verification on every batch
Dispatched next business day with cold-chain delivery
Temperature-controlled packaging from lab to door
Batch-specific Certificate of Analysis available on request

Quality Guaranteed

Every batch is HPLC-tested to ≥98% purity. Certificate of Analysis and SDS available on request.

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