
Buy PAL-GHK Research Peptide
PAL-GHK is available as a lyophilised powder, independently HPLC and MS-UPLC tested to ≥98% purity. A batch-specific Certificate of Analysis is available on request.

Buy PAL-GHK Research Peptide
PAL-GHK is available as a lyophilised powder, independently HPLC and MS-UPLC tested to ≥98% purity. A batch-specific Certificate of Analysis is available on request.
HPLC Verified
≥98% purity
Lyophilised
Powder format
Express Shipping
Cold-chain included
COA Available
Every batch
Same or Next Day Dispatch
Order before 12pm GMT for same-day dispatch; after 12pm ships next business day
HPLC Verified
≥98% purity
Lyophilised
Powder format
Express Shipping
Cold-chain included
COA Available
Every batch
Same or Next Day Dispatch
Order before 12pm GMT for same-day dispatch; after 12pm ships next business day
What is PAL-GHK?
A skin-penetrating peptide pairing the matrix-signalling GHK sequence with a fatty-acid chain, PAL-GHK is studied for its effects on collagen production in skin-cell models. Research focuses on how the lipid modification improves uptake while the tripeptide retains its collagen-stimulating activity.
- Studied in skin-cell cultures for its collagen-stimulating activity.
- Investigated for its improved uptake from the lipid modification.
- Examined for its matrikine signalling versus unmodified GHK.
- Used as a research tool in skin-model studies.
For research use only. Not intended for human use.
N-terminal conjugation of a palmitoyl fatty acid chain to the Gly-His-Lys tripeptide scaffold created a lipopeptide analogue investigated for its altered membrane interaction and cellular uptake properties. PAL-GHK, also known as Palmitoyl Tripeptide-1 or Palmitoyl-GHK (CAS 147732-56-7), carries the molecular formula C30H54N6O5 and a molecular weight of 594.79 g/mol. The C16 palmitoyl chain confers amphiphilic character absent in the parent GHK tripeptide. Produced via solid-phase peptide synthesis with subsequent lipid conjugation.
In vitro studies using human fibroblast monolayers have compared the capacity of Palmitoyl-GHK and unconjugated GHK to modulate collagen I and fibronectin gene expression. In vivo rodent models have explored the dermal retention and depot formation characteristics of Palmitoyl Tripeptide-1, investigating whether the palmitoyl chain confers prolonged local tissue residence.
Manufactured in a quality-controlled laboratory to a guaranteed purity of 98% or above. Every batch undergoes independent third-party testing using HPLC and MS-UPLC analysis before dispatch. Vials are vacuum sealed and stored in a temperature-controlled, monitored cold storage system. A batch-specific Certificate of Analysis is available on request.
Sold strictly for in vitro research purposes only. Not for human consumption. Intended for use by qualified researchers in laboratory settings only.
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Scientific review
Dr. Cristina Cosi
Scientific Contributor and Reviewer
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Every batch is HPLC-tested to ≥98% purity. Certificate of Analysis and SDS available on request.



