PAL-GHK
HPLC Verified

Buy PAL-GHK Research Peptide

PAL-GHK is available as a lyophilised powder, independently HPLC and MS-UPLC tested to ≥98% purity. A batch-specific Certificate of Analysis is available on request.

578.79 g/mol≥98% (HPLC)147732-56-7

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Order before 12pm GMT for same-day dispatch; after 12pm ships next business day

HPLC Verified

≥98% purity

Lyophilised

Powder format

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Cold-chain included

COA Available

Every batch

What is PAL-GHK?

A skin-penetrating peptide pairing the matrix-signalling GHK sequence with a fatty-acid chain, PAL-GHK is studied for its effects on collagen production in skin-cell models. Research focuses on how the lipid modification improves uptake while the tripeptide retains its collagen-stimulating activity.

  • Studied in skin-cell cultures for its collagen-stimulating activity.
  • Investigated for its improved uptake from the lipid modification.
  • Examined for its matrikine signalling versus unmodified GHK.
  • Used as a research tool in skin-model studies.

For research use only. Not intended for human use.

N-terminal conjugation of a palmitoyl fatty acid chain to the Gly-His-Lys tripeptide scaffold created a lipopeptide analogue investigated for its altered membrane interaction and cellular uptake properties. PAL-GHK, also known as Palmitoyl Tripeptide-1 or Palmitoyl-GHK (CAS 147732-56-7), carries the molecular formula C30H54N6O5 and a molecular weight of 594.79 g/mol. The C16 palmitoyl chain confers amphiphilic character absent in the parent GHK tripeptide. Produced via solid-phase peptide synthesis with subsequent lipid conjugation.

In vitro studies using human fibroblast monolayers have compared the capacity of Palmitoyl-GHK and unconjugated GHK to modulate collagen I and fibronectin gene expression. In vivo rodent models have explored the dermal retention and depot formation characteristics of Palmitoyl Tripeptide-1, investigating whether the palmitoyl chain confers prolonged local tissue residence.

Manufactured in a quality-controlled laboratory to a guaranteed purity of 98% or above. Every batch undergoes independent third-party testing using HPLC and MS-UPLC analysis before dispatch. Vials are vacuum sealed and stored in a temperature-controlled, monitored cold storage system. A batch-specific Certificate of Analysis is available on request.

Sold strictly for in vitro research purposes only. Not for human consumption. Intended for use by qualified researchers in laboratory settings only.

Scientific Review

Dr. Cristina Cosi

Scientific review

Dr. Cristina Cosi

Scientific Contributor and Reviewer

Currently under review

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£24.99
In Stock. Ships Next Business Day
Independent HPLC purity verification on every batch
Dispatched next business day with cold-chain delivery
Temperature-controlled packaging from lab to door
Batch-specific Certificate of Analysis available on request

Quality Guaranteed

Every batch is HPLC-tested to ≥98% purity. Certificate of Analysis and SDS available on request.

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