Buy Fragment 176-191 Research Peptide
Fragment 176-191 is available as a lyophilised powder, independently HPLC and MS-UPLC tested to ≥98% purity. A batch-specific Certificate of Analysis is available on request.
Buy Fragment 176-191 Research Peptide
Fragment 176-191 is available as a lyophilised powder, independently HPLC and MS-UPLC tested to ≥98% purity. A batch-specific Certificate of Analysis is available on request.
HPLC Verified
≥98% purity
Lyophilised
Powder format
Express Shipping
Cold-chain included
COA Available
Every batch
Same or Next Day Dispatch
Order before 12pm GMT for same-day dispatch; after 12pm ships next business day
HPLC Verified
≥98% purity
Lyophilised
Powder format
Express Shipping
Cold-chain included
COA Available
Every batch
Same or Next Day Dispatch
Order before 12pm GMT for same-day dispatch; after 12pm ships next business day
What is Fragment 176-191?
A synthetic 16-amino-acid peptide corresponding to the tail region of human growth hormone, HGH Fragment 176-191 is studied for fat-related metabolism without growth effects. Research focuses on the finding that it does not activate the growth hormone receptor or affect insulin-like growth factor signalling.
- Studied for its effects on lipolytic signalling in adipocyte models.
- Investigated for its lack of activity at the growth hormone receptor.
- Examined in research models for lipid metabolism without effects on IGF-1.
- Used as a research tool to study the lipolytic domain of growth hormone.
For research use only. Not intended for human use.
Isolation of a 16-amino acid C-terminal region from the full-length growth hormone sequence produced a peptide fragment with a distinct signalling profile. Fragment 176-191, also referred to as HGH Frag 176-191 (CAS 66004-57-7), carries the molecular formula C78H123N23O23S2 and a molecular weight of 1815.13 g/mol. Produced via solid-phase peptide synthesis.
In vitro studies using adipocyte cell models have investigated the compound's interaction with lipolytic signalling cascades, exploring whether HGH Frag 176-191 activates beta-adrenergic-adjacent pathways without engaging the JAK2/STAT5 axis. In vivo rodent models have examined the pharmacokinetic profile and tissue-specific distribution of the fragment relative to full-length recombinant growth hormone.
Manufactured in a quality-controlled laboratory to a guaranteed purity of 98% or above. Every batch undergoes independent third-party testing using HPLC and MS-UPLC analysis before dispatch. Vials are vacuum sealed and stored in a temperature-controlled, monitored cold storage system. A batch-specific Certificate of Analysis is available on request.
Sold strictly for in vitro research purposes only. Not for human consumption. Intended for use by qualified researchers in laboratory settings only.
Scientific Review
Scientific review
Dr. Cristina Cosi
Scientific Contributor and Reviewer
Currently under review
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Every batch is HPLC-tested to ≥98% purity. Certificate of Analysis and SDS available on request.